Cayo Santiago

ACCESS AND PERMISSION TO USE FACILITIES AT CAYO SANTIAGO

Cayo Santiago is supported by the National Center for Research Resources (NCRR). As such, we must abide the following guidelines established by NCRR (5/24/06).

"For each publication that results from grant support provided by the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), grantees must include an acknowledgment of support and a disclaimer stating the following:"

"The project described was supported by Grant Number CM-5 P40 RR003640-20 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH) and "Its contents are solely the responsibility of the authors and do not necessarily represent the official views of NCRR or NIH. "

Three steps:

1. Letter of intent to the Director (Dr. Edmundo Kraiselburd), Associate Director of the Center (Dr. Janis González-Martínez) and to the Resident Scientist of Cayo Santiago:Dr. Adaris Mas
   
   
2. Submit Proposal for CPRC review to the Associate Director and the Resident Scientist: Dr. Janis González-Martínez and Dr. Adaris Mas
   
   
3. Submit IACUC proposal and send copy to the Associate Director, the Resident Scientist and the Colony Manager: Dr. Janis González-Martínez, Dr. Adaris Mas , James Ayala
   
   

1. Letter of intent: Submit a letter of intent outlining project to the Associate Director of the Center and the Resident Scientist: Dr. Janis González-Martínez and Dr. Adaris Mas. If the project seems feasible and does not present a conflict of interest with on-going pursuits of investigators, The Resident Scientist will provide forthcoming dates of Institutional Animal Care and Use Committee (IACUC) meetings (and this can be found at http://committees.rcm.upr.edu/iacuc.html) and a full proposal is requested (NSF proposal format) to be sent to Dr. Janis González-Martinez and Dr. Adaris Mas. Appeals can be made to the CPRC Director: Dr. Edmundo Kraiselburd.

2. Submit Proposal for CPRC review: All scientists who plan to conduct research on Cayo Santiago are REQUIRED to submit proposals for their projects, (including pilot studies) a minimum of 60 days in advance of the proposed starting date. All proposals are reviewed by CPRC scientific staff and require approval by the CPRC and IACUC before any research can be conducted.
   
   Proposals are evaluated for scientific merit, feasibility, and potential overlap or conflict with other ongoing, funded or planned projects at the CPRC. In addition to CPRC staff, occasionally, additional outside investigators particularly those who have submitted, or initiated projects at the CPRC are consulted in the evaluation of a proposed project.
   
   Draft proposals are acceptable for the review providing they do not differ significantly from the final version. After revisions, the final version of the proposal must be sent to CPRC prior to the initiation of the project.
   
   Projects must be submitted for review well in advance of the start of a project. If funding (intramural or extramural) is sought, the proposal must be approved by the CPRC before it is submitted to a funding agency. Most funding agencies will not appropriate funds for projects without advance approval by the research facility (CPRC). In order to meet this obligation, all projects should be submitted to the CPRC 60 days in advance of the grant deadline.

   
   

   REQUIREMENTS FOR PROPOSALS

   The following items are essential for any proposal for review by the CPRC:

   • Hypotheses or purpose of project
     
     
   • Background and significance
     
     
   • Materials and methods
     
     
   • Budget (including CPRC bench fees Bench Fee and Invoicing)
     
     
   • Copy of Application forms for the Institutional Animal Care and Use Committee (IACUC) of the University of Puerto, Medical Science Campus for all live animal studies (including behavioral studies.)

   The materials and methods of a proposal should indicate the species, sex, ages and number of animals to be studied. It must clearly describe the procedures to be performed, e.g. intramuscular injections, venopuncture; list of measurements to be obtained, etc. It must also include medicaments required for anesthesia, including dosage.
   
   All submitted proposals must contain a budget that includes CPRC fees before receiving final CPRC approval. A CPRC bench (use) fee, a handling or per sample fee and/or per diem for all monkeys in the study is charged for all projects.
   
   

3. Submit IACUC proposal and send copy to the Associate Director, the Resident Scientist and the Colony Manager

• Submit proposal to IACUC.
  
  
• Send copy with signed signature page to Associate Director, the Resident Scientist, and the Colony Manager by email (Dr. Janis González-Martinez), (Dr. Adaris Mas), (James Ayala).
  
  

All researchers whose projects involve the study of live animals (including auditory and digital recordings) must also submit their full proposals for independent evaluation by the Institutional Animal Care and Use Committee (IACUC) of the University of Puerto Rico, Medical Sciences Campus, and their home institution. The appropriate forms for the UPR-RCM-IACUC are available http://committees.rcm.upr.edu/iacuc.html

Submit proposal to: Institutional Animal Care and Use Committee

University of Puerto Rico, Medical Sciences Campus
PO Box 365067, San Juan, Puerto Rico 00936-5067
Tel: (787) 282-0031

The Institutional Animal Care and Use Committee (IACUC) of the Medical Science Campus is responsible for the review of all animal care, research, breeding and educational/training protocols involving the use of monkeys at the CPRC. The IACUC then passes judgment on the proposal with special emphasis on whether or not the project meets USPHS policy on the humane care and use of animals and the USDA regulations established under The Animal Welfare Act, as amended. The IACUC may vote to approve, disapprove, defer a decision pending further information or an interview with an investigator, or approve the project conditionally if the investigator agrees to make the suggested changes in the protocol. If the committee feels that more information is needed or modifications of the proposal are necessary, the investigator will be contacted in writing and the project is re-reviewed the following meeting. Only after a proposal has been reviewed and approved, can it start.