Caribbean Primate Research Center

Staff Members- Associate Investigator

Anil Kumar, Ph.D.
Associate Investigator
Caribbean Primate Research Center
Professor, Ponce School of Medicine


Our laboratory is involved in studies associated with pathogenesis, immunology and effect of substance abuse in macaque model of AIDS. One of the project in the laboratory deals with effect of opiate on disease progression and vaccine-induced immune responses in SHIV/macaque model of AIDS. The second project in lab deals with drug holidays in SHIV-infected macaques and determines whether drug holidays offer any immunoloigcal advantage over continuous anti-retroviral treatment.

Research Support

1. RO1 DA 15013-02, 09-19-2001 to 02-28-2005
   Effects of opiate on virus/host responses in SHIV/macaque
   
   
2. SO6 GM008239-18S2, 06-01-03 to 05-31-05
   Structured Antiretroviral Treatment in SHIV/Macaques
   
   
3. Internal CPRC funding
   
   

Representative Publications

1. Anil Kumar (2003). Tenofovir disoproxil fumarate. Drugs. 63:1609-1610
   
   
2. Anil Kumar, S Mukherjee, J Shen, S Buch, Z Li, I Adany, Z Liu, W Zhuge, M Piatak, J lifson, H. McClure and O Narayan (2002) Immunization of mavcaques with live SHIV vaccines conferred long-term protection and sterilizing immunity against mucosally inoculated homologous and heterologous challenge viruses. Virology 301:189-205.
   
   
3. S. Buch, F. Villinger, D. Pinson, Y. Hou, I. Adany, Z. Li, R. Raghavan, Anil Kumar and O. Narayan (2002). Innate differences between simian human immunodeficiency virus (SHIVKU-2) infected rhesus and pig-tailed macaques in development of neurological disease. Virology 295:54-62.
   
   
4. Andrey Hicks, R.Potula, Y Sui, F Villinger, D Pinson, I Adany, Z Li, C Long, P Cheney, J Marcario, F Novembre, N Mueller, Anil Kumar, E Major, O Narayan and S Buch (2002) Neuropathogenesis of Lentiviral Infection in Macaques: Roles of CXCR4 and CCR5 viruses and IL-4 in Enhancing MCP-1 Production in Macrophages. Am J. Pathol. 161:813-822.